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Epistasis occurs when the phenotype expression of one gene is influenced by another gene. Example: Gene A must be present for Gene B to express a certain trait. Example: The coat color in mice is a classic example。

Epistasis is fundamental to the structure and function of genetic pathways and to the evolutionary dynamics of complex genetic systems. High-throughput functional genomics, systems-level ...

We assessed the epitasifunctional impact of the epistasis signals across a range of functional/-omics datasets identifying significant single-variant eQTLs across brain tissues,。

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